TRAMINEX

Traminex is an injectable product from Nexus Pharma that contains tranexamic acid, used to treat skin pigmentation issues like melasma and hyperpigmentation. Originally developed to control bleeding, tranexamic acid works in dermatology by reducing melanin production. Each ampoule contains 250mg and is administered via IV or IM injection. It’s approved by South Korea’s Ministry of Food and Drug Safety. While generally safe under medical supervision, it may cause side effects like nausea or dizziness and isn't suitable for people with a history of blood clots.

How and When to Use Traminex (Tranexamic Acid) in Aesthetic or Dermatologic Settings:

How to Use It:

  • Dose: Typically, 250 mg per ampoule (5 mL). Most protocols use 250–500 mg per session, depending on the patient and indication.

  • Route: Intravenous (IV) slow push or intramuscular (IM) injection.

  • Frequency: Commonly once a week for several weeks, but it can vary depending on the skin condition and desired outcome.

When to Use It:

  • Best used in treatment regimens for melasma, PIH (post-inflammatory hyperpigmentation), or general skin brightening, often alongside topical treatments or oral agents.

  • Not a one-time fix—consistent sessions are typically needed for noticeable improvement.

Can You Add It to an IV Drip?

Yes, tranexamic acid can be added to an IV drip, but with caution:

  • Mixing: It must be compatible with the components of your IV drip. Usually, it's mixed with normal saline or dextrose, but avoid mixing with anything acidic or unstable like Vitamin C unless compatibility is confirmed.

  • Stability: Tranexamic acid is stable in solution but should be used soon after mixing. Follow your clinic’s sterile compounding protocols.

  • Professional Oversight: Should only be done under the guidance of a licensed medical professional who understands both IV compounding and the patient’s health profile.

Important Considerations:

  • Do not self-administer. This is a prescription-only treatment and should be performed by trained medical staff.

  • Avoid if you have a history of thrombosis, are pregnant without doctor approval, or are on certain medications like hormonal contraceptives.

  • Monitor for side effects like GI discomfort, headaches, or dizziness.